Chongqing Peg-Bio Biopharm Co., Ltd.

1 Product Details

Chinese name:Recombinant Lysyl Endopeptidase English name:Recombinant Lysyl Endopeptidase (rLys-C)

CAS:72561-05-8                                  Brand:IMED

Place of Origin:Chongqing                 Storage Condition:-15℃

Purity:>96%                                        Product Category:Recombinant Protease

Grade:Pharmaceutical grade              Alias:Recombinant lysyl endonuclease

Specification:1mg/branch,10mg/branch,0.5g/bottle

Main Uses:In the field of biomedical industry, rLys-C is used in the production and preparation of peptides and insulin analogs, such as Mentholatum, Ditropan, Degulin, etc.; in the field of scientific research, it is used in the study of proteomics, sequencing of peptides, identification of phosphorylated peptides, analysis of disulfide bonds, analysis of N-glycans and so on.

2 Product Description

Lysyl Endopeptidase (LysylEndopeptidase or Achromobacterprotease I, EC 3.4.21.50) is a serine

 protease that specifically recognizes and cleaves the peptide bond at the carboxyl end of Lys 

in peptide chains. Recombinant lysyl endopeptidase (rLys-C) produced by Chongqing IMED 

is selected from Achromobacterlyticus. source and prepared by using E. coli recombinant table,

 and its enzyme activity properties are consistent with natural Lys-C.

The product FDA DMF has been filed: 039016.

3 Quality standard

4 Product Advantages

• Compared with Lys-C from Pseudomonas aeruginosa and other sources, this product has

  a higher enzymatic efficiency at PK and DK sites; 

• Recombinant expression preparation, without the risk of residual heterozymes such as

  Lys-N and Arg-C; 

• No animal source materials are used in the production process, no risk of exogenous

  virus contamination; 

• 3000L fermentation scale production line, annual output of not less than 8kg; verified by

  multiple batch production, highly consistent quality between batches; 

• The production workshop is operated according to GMP, and the production equipment,

  environment and process control are implemented with reference to the Good Manufacturing Practice (GMP); 

• Complementary rLys-C protease trace residue detection kit is available; 
  

• DMF has been filed: 039016, and relevant regulatory support documents can be provided

  according to customer requirements; 
  

• Customized packaging specifications are available according to customer requirements.

5 Packaging and transportation

This product is in the form of lyophilized powder, packaged in HDPE bottles for oral medication, which is convenient for transportation and storage; it can be stored for at least 2 years under -15℃. The whole process of cold chain transportation, the whole temperature monitoring from leaving the warehouse to receiving the goods.